Kert Viele @KertViele Introduction We conduct clinical trials to find effective treatments. Much...Read More
Hypothesis testing, clinically important effects, and do we pay too much for clinical trial insurance?
@KertViele Highly powered clinical trials are expensive. The sample sizes involved are a sum of...Read More
Kert Viele (With thanks to Jeff Wetherington, Helen Zhou, Anna McGlothlin, and Liz Krachey) You are starting a development program. While currently unknown to you, your novel therapy is effective, at least at the right dose. In...Read More
Kert Viele and Christina Saunders @KertViele My colleague Scott Berry recently presented a webinar on historical borrowing. https://ictr.wpengine.com/webinar-5-historical-borrowing-in-clinical-trials/ This blog post doesn’t...Read More
Real world evidence is everywhere these days, bolstered primarily by the FDA motivated discussion of including real world evidence as a supplement or complete replacement of control arms in clinical trials (e.g. synthetic...Read More